研究创新团队

食品绿色制造与安全控制研究团队

发布日期:2016-04-13     作者:      分享到:

团队组长:杨兴斌教授

团队成员:孔庆军、邵红军、张忠、李照、林德慧

 

 

一.团队成员

陕西师范大学食品绿色制造与安全控制研究团队成立于2015年,是新万博注册页面的一支重要科研与教学队伍。团队在组长杨兴斌教授带领下,拥有5名优秀专业人才,包括教授1名、副教授2名,讲师2名,师资博士后1名。团队拥有中青年科技创新领军人才各1人,3人有出国学习与研究经历,形成了一支多学科交叉融合、以中青年人才为主体、自主创新能力强、富有团队精神的高水平人才队伍。

本研究团队是一支科研与教学相结合、基础与应用相结合、食品科学与化学、生命科学相结合的创新研究团队。着力扎根西部,服务于区域经济社会的发展。团队将科研目光定位于关系民生、民族繁衍的食品绿色制造及食品安全控制的科学前沿问题,以高值化食品的绿色制造技术、功能(保健)食品及食品安全全程控制为发展目标,提升大众的公共营养与食品安全科学认知水平,促进食物绿色加工安全和营养改善。目前,团队在食品绿色加工、生物制造、食品安全检测与控制、营养代谢与保健食品研发领域具有较强竞争力,处于国内领先地位。

.研究方向和特色

食品绿色制造主要围绕西北及陕西大宗和特色农产品及食品的化学、营养、安全及加工开展创新研发工作。主要致力于特色农产品的营养聚集化节能减排和综合利用的绿色精深加工、功能(保健)食品的产业化、酶学及蛋白工程产品的绿色生物制造,以及食品功能因子的分子营养,食品功能成分互作特性及分子机制等基础理论的系统前沿研究。同时,以食品加工及生产过程中的全程安全监测与控制为发展目标,针对食品生产、加工过程中存在的农兽药、激素、生物毒素、食物过敏原、非食用添加物、食源性致病菌等有害物质带来的安全问题与健康风险,综合运用多学科现代科学理论与技术,对影响食品质量安全的控制及检测关键技术进行深入研究,重点在检测技术、质量控制与典型示范三个方面开展食品中化学污染物高通量侦测技术研究,常见病原微生物检测和溯源技术和农产品食品危害因子风险甄别与控制技术研究,创新性开发一批在线检测技术、设备、信息系统和标准规范,并进行技术集成示范。具体几个主要研究方向如下:

1.食物寡糖、多糖的化学结构与功能研究

(1)寡糖与多糖和糖肽的分离、化学结构鉴定与胶体化学

(2)功能糖的生物功能与分子营养机制

(3)功能糖与类黄酮等小分子的营养互作特性及复方保健食品开发

(4)西部特色食品与马铃薯主食食品的研发与制造

2.食品安全检测与控制

(1)多糖基纳米安全检测技术、分子印迹技术的开发

(2)荧光探针的合成及在食品安全检测的应用

(3)色谱-质谱联用检测技术在食品安全中的应用

3.食品中生物毒素代谢

(1)致病菌侵染水果等食品中生物毒素代谢组学研究

(2)食品中生物毒素与营养品质因子互作代谢组学研究

4.有害物的生成机制及控制技术

(1)食品污染物健康效应的毒性通路与分子毒理机制研究

(2)食品中生物毒素合成及调控研究

(3)食品中生物毒素关键基因筛选及功能验证研究

5.食品酶学及工业极端酶生物制造

(1)EGF等工程菌的构建及食品酶制剂、植物酵素的生物制备

(2)酶结构解析及功能研究

(3)生物化妆品及保健食品酶制剂开发

6.食品分子组装及保鲜膜大分子纳米材料

(1)多糖基食品功能因子稳态化与生物增效系统

(2)功能糖的纳米加工工艺及靶向输送系统分子设计及制造

(3)多糖基食品保鲜膜的基础理论及产品开发

(4)多糖大分子化妆品基材及多肽、酶制剂生物化妆品开发

三.研究条件

团队建设的平台所在单位为新万博注册页面,以及“陕西省食品绿色加工与安全控制”工程实验室、教育部“药用资源与天然药物化学”重点实验室和“西北濒危药材资源开发”国家工程实验室。实验室拥有GC/MS-QP2010气-质联用仪(GC-MS)、Agilent 6460 LC/MS 三重四级杆液质联用仪、micrOTOF-Q III 高性能的电喷雾-四级杆-飞行时间LC/MS/MS串联质谱仪(UPLC-Q-TOF-MS/MS)、HPLC仪5台、半制备色谱仪1台、ECO PHYSICS CLD66型NO仪等现代实验仪器。

团队研究室按国家重点实验室和国家及省部级工程中心的标准而建设,研究团队拥有国内先进的食品化学、安全与营养研究平台,先后建立了设备先进和管理规范的功能食品工程实验室(含细胞实验室和动物实验室)、食品生物工程实验室、食品质量与安全检测实验室、食品加工中试与生产示范车间四大专业研究平台。具备食品化学、安全与营养研究以及功能食品研发转化所需的高水平实验评价技术平台,满足承担国家和省级重大研究任务的实验平台需求。

四.团队成员简介

杨兴斌,博士,新万博注册页面院长、教授、博士生导师,教育部“药用资源与天然药物化学”重点实验室和“西北濒危药材资源开发”国家工程实验室学术带头人,陕西省食品绿色加工与安全控制工程实验室主任。先后在Antioxid. Redox Signal.(IF 8.2), Am. J. Clin. Nutr. (IF 6.5), Free Radic. Biol.Med.(IF 5.7), Mol. Nutr.Food Res., PLoS ONE, J. Agric. Food Chem., Food Func., Food Chem.等SCI杂志发表论文70余篇,IF>5论文5篇,论文被SCI引用900余次,论文H-index为18。担任《食品科学》、《食品安全质量检测学报》、《陕西师范大学学报》、《Nutrition and Dietetics》、《International Journal of Food Science, Nutrition and Dietetics》等杂志编委。兼任陕西省食品科学技术学会副理事长、陕西省营养学会副理事长。先后获陕西省科技进步一、二等奖各1项和陕西高等学校科学技术一等奖2项,2011年获中国食品产业产学研创新发展杰出科研人才奖,2013年获陕西省职工优秀科技“创新人物”称号,2014年荣获“全国模范军队转业干部”称号及省部级劳动模范,2014年入选“陕西省中青年科技创新领军人才”。

研究方向:

(1)食品营养化加工和保健食品方面的产学研应用基础研究;

(2)食品营养与代谢;

(3)食品安全与纳米检测。

孔庆军,男,1976年9月20日生,浙江大学化学专业博士,现为新万博注册页面副教授、硕士生导师,2014年按“学术骨干”引进陕西师范大学。目前主持国家自然科学基金1项,参加国家自然科学基金3项,先后发表学术论文15余篇,其中SCI收录杂志发表论文8篇。

邵红军:1977年出生,博士,副教授,硕士生导师。主持高等学校博士学科点专项科研基金新教师基金、中国博士后科学基金一等资助、陕西省农业科技攻关计划等多项省部级项目。在国内外期刊如J Antibiot、J Sci Food Agric、 HeterocyclesHel、Chim Acta等上发表文章30余篇。

研究方向:

(1) 食药资源化学与分子营养研究;

(2)马铃薯主食化食品研究与开发。

张忠,男,1987年出生,博士,讲师。2015年7月博士毕业于中国科学院烟台海岸带研究所。2015年获“中国科学院院长优秀奖”,主持和参加多个科研项目。近年来在J. Mater. Chem. A,ACS Appl. Mater. Interfaces,J. Agric. Food. Chem.等发表SCI论文17篇,其中第一作者7篇;一区论文4篇。

研究方向

(1)新型表面子印迹聚合物的制备及其样品前处理与传感中的应用;

(2)食品中植物生长调节剂的分析与检测。

李照,女,1986年出生,博士,讲师。2014年7月博士毕业于中国科学院化学研究所。目前主持中央高校基本科研业务费专项资金项目1项。近年来在Anal. Chem., Chem. Commun.和Biosens. Bioelectron.等国际重要期刊上发表SCI论文10余篇,还申请了三项专利。

研究方向

(1)荧光探针的设计合成及其在食品质量安全检测中的应用。

(2)食品危害物安全控制技术研究。

林德慧, 1985年出生,博士,师资博后。2015年7月博士毕业于西北农林科技大学,期间于昆士兰大学联合培养2年(2013/01-2015/02)。目前主持全国博士后面上项目1项、中央高校基本科研业务费专项项目1项。近年来发表学术论文8篇,其中在Bioresour. Technol.,Food Hydrocolloids,Carbohyd. Polym.等期刊发表4篇(SCI一区1篇,二区2篇,三区1篇)。

研究方向:

(1)微生物导向的胞外多糖的原位组装及其构效关系研究;

(2)可食性多糖基纳米保鲜膜的开发与应用。

五.团队代表性成果

1.课题组负责人:杨兴斌教授

5年研究成果:

1)奖励与专利

[1]杨兴斌,任道远,张海生,李婷,田灵敏,时晓龙,何念武,王东营,孙延飞。天然多糖及寡糖的色谱质量控制技术构建与生物功能研究,食物类黄酮与功能糖的化学与分子营养的应用基础研究。获陕西高校科学技术一等奖,陕西省教育厅,2016年。

[2]杨兴斌,赵燕,吕游,何念武,田灵敏。天然多糖及寡糖的色谱质量控制技术构建与生物功能研究,获陕西省科学技术进步二等奖,陕西省人民政府,2014年。

[3]杨兴斌,赵燕,田灵敏,吕游,王东营,何念武,焦亚东。天然多糖及寡糖的色谱质量控制技术构建与生物功能研究,陕西高等学校科学技术一等奖,陕西省教育厅,2013年。

[4]杨兴斌,赵燕,何念武,王东营,田灵敏。一种紫阳富硒绿茶含硒多糖及其制备方法和用途,发明专利,2013年,中国人民共和国国家知识产权局,ZL201110293739.2

[5]杨兴斌,赵燕,何念武,王东营。一种协同降血脂的双层缓释片,发明专利,2013年,中国人民共和国国家知识产权局,ZL201110382887.1

2基金项目

[1] 果蔬硝酸盐与类黄酮在血管内皮功能调节中的营养机制探究,国家自然科学基金面上项目(C31171678) ,2012-2015,主持。

[2] 食品检验中糖类标识组合型指纹色谱质控技术的构建,国家自然科学基金面上项目(C30972054),2010-2012,主持。

[3] 陕西特色农产品绿色加工与安全控制研究,陕西省发展改革委员会平台建设项目(1503070043, 300万),主持。

[4] 富硒茶与地黄资源的高值化利用及功能食品开发,陕西省科技统筹创新工程计划战略性新兴产业重大产品(群)(2015KTCQ02-01),2015-2017,主持。

[5] 陕西特色茶产品开发的关键技术研究与产业化示范,中央高校基本科研业务费陕西师范大学创新团队项目(GK201501006),2015-2017,主持。

[6] 天然类黄酮及其衍生物的代谢动力学与血管营养机制,中央高校基本科研业务费陕西师范大学特别支持项目(GK201103004),2012-2014,主持。

3荣誉称号

2014年入选陕西省中青年科技创新领军人才推进计划

2014年荣获全国模范军队转业干部称号(中共中央组织部等四部委“国转联[2014]4号文件”联合授予)

2013年获陕西省职工优秀科技创新人物称号

2011年获中国食品产业产学研创新发展杰出科研人才奖

4代表论文

1. Wenfeng Li, Di Huang,Anning Gao,Xingbin Yang*. Stachyose increases absorption and hepatoprotective effect of tea polyphenols in high fructose-fed mice.Molecular Nutrition and Food Research,2016, 60, 502-510 (SCI一区, IF 4.603)

2. Yuanyuan Hu, Zuoxu Hou, Dongyang Liu,Xingbin Yang*. Tartary buckwheat flavonoids protect hepatic cells against high glucose-induced oxidative stress and insulin resistance via MAPK signaling pathways.Food & Function,2016, (SCI一区, IF 2.791)

3. Xiao Han, Shan Deng, Ning Wang, Yafei Liu,Xingbin Yang*. Inhibitory effects and molecular mechanisms of tetrahydrocurcumin against human breast cancer MCF-7 cells.Food & Nutrition Research,2016, 60, 30616(SCI二区, IF 2.162)

4.Wenfeng Li,Nianwu He,*Lingmin Tian,Xiaolong Shi,Xingbin Yang*. Inhibitory effects of polyphenols-enriched extract from Ziyang tea against human breastcancer MCF-7 cells through ROS-dependent mitochondria molecular mechanism.Journal of Food and Drug Analysis,2016, online (SCI, IF 0.625)

5. Wenfeng Li, Li Yuan, Xuling Xiao,Xingbin Yang*.Dehydration of kiwifruit (Actinida deliciosa) slices using heat pipe combining with impingement technology.International Journal of Food Engineering,2016, online (SCI, IF 0.497)

6. Wenfeng Li, Ruijun Zhang, Jianjun Guo, Hongjun Shao?,Xingbin Yang?. Protective effect ofR. glutinosaoligosaccharides against highl-carnitine diet-induced endothelial dysfunction and hepatic injury in mice.International Journal of Biological Macromolecules,2016, 85, 285-293 (SCI, IF 2.858)

7. Daoyuan Ren, Ning Wang, Jianjun Guo, Li Yuan?,Xingbin Yang?. Chemical characterization ofPleurotus eryngiipolysaccharide and its tumor-inhibitory effects against human hepatoblastoma HepG-2 cells.Carbohydrate Polymers,2016, 138, 123-133 (SCI, IF 4.074)

8.Yuanyuan Hu, Yan Zhao*, Daoyuan Ren, Jianjun Guo, Yiyang Luo,Xingbin Yang*.Hypoglycemic and hepatoprotective effects of D-chiro-inositol-enriched tartary buckwheat extract in high fructose-fed mice.Food & Function,2015, 6 (12), 3760-3769 (SCI一区, IF 2.791)

9.Yuanyuan Hu, Yan Zhao, Li Yuan,Xingbin Yang*.Protective effects of tartary buckwheat flavonoids on high TMAO diet-induced vascular dysfunction and liver injury in mice.Food & Function,2015, 6 (10), 3359-3370 (SCI一区, IF 2.791)

10. Daoyuan Ren, Yuanyuan Hu, Yiyang Luo,Xingbin Yang*.Selenium-containing polysaccharide from Ziyang green tea ameliorates high-fructose diet induced insulin resistance and hepatic oxidative stress in mice.Food & Function,2015, 6 (10), 3342-3350 (SCI一区, IF 2.791)

11. Wenfeng Li, Moyi Wang, Xulin Xiao*, Baoshan Zhang,Xingbin Yang*. Effects of air-impingement jet drying on drying kinetics, nutrient retention and rehydration characteristics of onion (Allium cepa) slices.International Journal of Food Engineering,2015, 11(3), 435-446 (SCI, IF 0.497)

12. Jianjun Guo, Yonghong Meng, Yan Zhao, Yuanyuan Hu, Daoyuan Ren,Xingbin Yang*. Myricetin derived fromHovenia dulcis Thunb.ameliorates vascular endothelial dysfunction and liver injury in high choline-fed mice.Food & Function,2015, 6, 1620-1634 (SCI一区, IF 2.791)

13. Yan Nie, Daoyuan Ren, Xinshan Lu, Yanfei Sun,Xingbin Yang*. Differential protective effects of polyphenols extracts from apple peels and fleshes against acute CCl4-induced liver damage in mice.Food & Function,2015, 6, 513-524 (SCI二区, IF 2.791)

14.Daoyuan Ren, Yan Zhao, Yan Nie, Xinshan Lu, Yanfei Sun,Xingbin Yang*. Chemical composition ofPleurotus eryngiipolysaccharides and their inhibitory effects against high-fructose diet-induced insulin resistance and oxidative stress in mice.Food & Function,2014, 5, 2609-2620 (SCI一区, IF 2.791)

15. Dongying Wang, Yan Zhao, Yanfei Sun,Xingbin Yang*.Protective effects of Ziyang tea polysaccharides on CCl4-induced oxidative liver damage in mice.Food Chemistry,2014, 143, 371-378 (SCI 二区, IF 3.391)

16. Daoyuan Ren, Yan Zhao, Yan Nie, Nana Yang,Xingbin Yang*. Hypoglycemic and hepatoprotective effects of polysaccharides fromArtemisia SphaerocephalaKrasch seeds.International Journal of Biological Macromolecules,2014, 69, 296-306 (SCI, IF 2.858)

17. Ning Wang, Daoyuan Ren, Shan Deng,Xingbin Yang*. Differential effects of baicalein and its sulfated derivatives in inhibiting proliferation of human breast cancer MCF-7 cells.Chemico-Biological Interactions,2014, 221, 99-108 (SCI, IF 2.577)

18.Xingbin Yang, Catherine P Bondonno, Adeline Indrawan, Jonathan M Hodgson, Kevin D Croft*. An improved mass spectrometry based measurement of NO metabolites in biological fluids.Free Radical Biology & Medicine,2013, 56, 1-8 (SCI二区, IF 5.710)

19. Xiaolong Shi, Yan Zhao, Yadong Jiao, Tengrui Shi,Xingbin Yang*. ROS-dependent mitochondria molecular mechanisms underlying antitumor activity ofPleurotus abalonusacidic polysaccharides in human breast cancer MCF-7 cells.PloS ONE,2013, 6(5), e64266(SCI二区, IF 3.534)

20. Nianwu He, Xiaolong Shi, Yan Zhao,Lingmin Tian, Dongying Wang,Xingbin Yang*. Inhibitory effects and molecular mechanisms of selenium-containing tea polysaccharides on human breast cancer MCF-7 cells.Journal of Agricultural and Food Chemistry,2013, 61(3), 579-588 (SCI一区, IF 3.107)

21. Ruijun Zhang, Yan Zhao, Yanfei Sun, Xinshan Lu,Xingbin Yang*. Isolation, characterization, and hepatoprotective effects of the raffinose family oligosaccharides fromRehmannia glutinosaLibosch.Journal of Agricultural and Food Chemistry, 2013, 61(32), 7786-7793 ( SCI一区, IF 3.107)

22. Ting Li, Xinshan Lu,Xingbin Yang*. Stachyose-enrichedα-galacto-oligosaccharides regulate gut microbiota and relieve constipation in mice.Journal of Agricultural and Food Chemistry, 2013, 61(48),11825-11831 (SCI一区, IF 3.107)

23. Ting Li, Jiao Zhu,Ling Guo, Xiaolong Shi,Yafei Liu,Xingbin Yang*. Differential effects of polyphenols-enriched extracts from hawthorn fruit peels and fleshes on cell cycle and apoptosis in human MCF-7 breast carcinoma cells.Food Chemistry,2013, 141(2), 1008-1018 (SCI二区, IF 3.259)

24. Xinshan Lu, Yan Zhao, Yanfei Sun, Su Yang,Xingbin Yang*. Characterization of polysaccharides from green tea ofHuangshan Maofengwith antioxidant and hepatoprotective effects.Food Chemistry,2013, 141(4), 3415-3423(SCI二区, IF 3.259)

25.Xingbin Yang, Su Yang, Yurong Guo, Yadong Jiao, Yan Zhao*.Compositional characterization of soluble apple polysaccharides, and their antioxidant and hepatoprotective effects on acute CCl4-caused liver damage in mice.Food Chemistry,2013, 138(2-3), 1256-1264 (SCI二区, IF 3.259)

26. Yanfei Sun,Xingbin Yang*, Xinshan Lu, Dongying Wang, Yan Zhao*. Protective effects of Keemun black tea polysaccharides on acute carbon tetrachloride-caused oxidative hepatotoxicity in mice.Food and Chemical Toxicology,2013, 58, 184-192 (SCI二区, IF 2.610)

27.Xingbin Yang*, Yan Zhao. Absorption and metabolism of red wind polyphenols and their potential health benefits in cardiovascular function.TheAmerican Journal of Clinical Nutrition,2012, 95(6), 1496-1497 (SCI一区, IF 6.504)

28.Lingmin Tian, Xiaolong Shi, Linhong Yu, Jiao Zhu, Rui Ma,Xingbin Yang*.Chemical composition and hepatoprotective effects of polyphenol-rich extract fromHouttuynia cordatatea.Journal of Agricultural and Food Chemistry,2012, 60(18), 4641-4648 (SCI一区, IF 2.906)

29.Nianwu He,Xingbin Yang*, Yadong Jiao, Lingmin Tian,Yan Zhao*.Characterization of antioxidant and antiproliferative acidic polysaccharides from Chinese wolfberry fruits.Food Chemistry,2012, 133(3), 978-989 (SCI二区, IF 3.334)

30.Haisheng Zhang, Min Zhang, Linhong Yu, Yan Zhao, Nianwu He,Xingbin Yang*. Antitumor activities of quercetin and quercetin-5",8-disulfonate in human colon and breast cancer cell lines.Food and Chemical Toxicology,2012, 50(5), 1589-1599 (SCI二区, IF 3.01)

31.Dongying Wang, Yan Zhao, Yadong Jiao, Linhong Yu, Su Yang,Xingbin Yang*. Antioxidative and hepatoprotective effects of the polysaccharides fromZizyphus jujube cv.Shaanbeitanzao.Carbohydrate Polymers,2012, 88(4), 1453-1459 (SCI, IF 3.479)

32.Nian-Wu He, Yan Zhao,Ling Guo,Jun Shang,Xing-Bin Yang*. Antioxidant, antiproliferative and pro-apoptotic activities of a saponin extract derived from the roots ofPanax notoginseng(Burk.) FH. Chen.Journal of Medicinal Food,2012, 15(4), 350-359 (SCI, IF 1.642)

33.Xingbin Yang*. Comments for “Cancer: Solving an age-old problem”.Nature,2012, 483, S2-S6 (SCI, IF 38.597) (学术交流)

34.Xingbin Yang*. Comments for “Prevention: Nipped in the bud”.Nature,2012, 485, S18-S19 (SCI, IF 38.597) (学术交流)

35.Lingmin Tian, Yan Zhao, Chao Guo,Xingbin Yang*. A comparative study on the antioxidant activities of an acidic polysaccharide and various solvent extracts derived from herbalHouttuynia cordata.Carbohydrate Polymers,2011, 83(2), 537-544 (SCI, IF 3.628)

36.Xingbin Yang, Kevin D Croft, Ya P Lee, Trevor A Mori, Ian B Puddey, Sofia Sipsas, Anne Barden, Ewald Swinny, Jonathan M Hodgson*. The effects of a lupin-enriched diet on oxidative stress and factors influencing vascular function in overweight subjects.Antioxidants and Redox Signaling,2010, 13(10), 1517-1524 (SCI二区, IF 8.209)

37.Xingbin Yang, Yan Zhao, Nianwu He, Kevin D. Croft*. Isolation, characterization, and immunological effects of α-galacto-oligosaccharides from a new source, the herbLycopus lucidusTurcz.Journal of Agricultural and Food Chemistry,2010, 58(14), 8253-8258 (SCI一区,IF 2.816)

38.Xingbin Yang, You Lv, Lingmin Tian, Yan Zhao*. Composition and systemic immune activity of the polysaccharides from an herbal tea (Lycopus lucidusTurcz).Journal of Agricultural and Food Chemistry,2010, 58(10), 6075-6080(SCI一区, IF 2.816)

39.Daoyuan Ren, Yadong Jiao,Xingbin Yang, Li Yuan, Jianjun Guo, Yan Zhao*. Antioxidant and antitumor effects of polysaccharides from the fungusPleurotus abalonus.Chemico-Biological Interactions2015,237(2015),166-174 (SCI三区, IF 2.577)

40.Shufang Yang, Haisheng Zhang*,Xingbin Yang, Yilin Zhu, Min Zhang. Evaluation of antioxidative and antitumor activities of extracted flavonoids from Pink Lady apples in human colon and breast cancer cell lines.Food & Function,2015, 6 (12), 3789-3798 (SCI一区, IF 2.791)

41. Daoyuan Ren, Yadong Jiao,Xingbin Yang, Li Yuan, Jianjun Guo, Yan Zhao. Antioxidant and antitumor effects of polysaccharides from the fungusPleurotus abalonus.Chemico-Biological Interactions,2015, 237, 166-174 (SCI, IF 2.577)

42.Yanmang Cui,Xingbin Yang, Xinshan Lu, Jinwen Chen, Yan Zhao. Protective effects of polyphenols-enriched extract from Huangshan Maofeng green tea against CCl4-induced liver injury in mice.Chemico-Biological Interactions,2014, 220, 75-83 (SCI, IF 2.577)

43. Catherine P Bondonno, Alex H Liua, Kevin D Croft, Natalie C Ward,Xingbin Yang, Michael J Considine, Ian B Puddey, Richard J Woodman, Jonathan M Hodgson. Short-term effects of nitrate-rich green leafy vegetables on blood pressure and arterial stiffness in individuals with high-normal blood pressure.Free Radical Biology & Medicine,2014, 77, 353-362 (SCI二区, IF 5.736)

44.Yan Zhao*,Xingbin Yang, Daoyuan Ren, Dongying Wang, Yang Xuan. Preventive effects of jujube polysaccharides on fructose-induced insulin resistance and dyslipidemia in mice.Food & Function,2014, 5, 1771-1778 ( SCI二区, IF 2.791)

45. Catherine P. Bondonno, Luke A. Downey, Kevin D. Croft, Andrew Scholey, Con Stough,Xingbin Yang, Michael J. Considine, Natalie C. Ward, Ian B. Puddey, Ewald Swinny, Aidilla Mubarak,Jonathan M. Hodgson. The acute effect of flavonoid-rich apples and nitrate-rich spinach on cognitive performance and mood in healthy men and women.Food & Function,2014, 5, 849-858 (SCI二区, IF 2.781)

46. Yuanyuan Hu, Tong Wang,Xingbin Yang, Yan Zhao*.Analysis of compositional monosaccharides in funguspolysaccharides by capillary zone electrophoresis.Carbohydrate Polymers,2014,102, 481-488 (SCI, IF 4.074)

47. Yanmang Cui, Yong Han,Xingbin Yang, Yanfei Sun, Yan Zhao. Protective effects of quercetin and quercetin-5",8-disulfonate against carbon tetrachloride-caused oxidative liver injury in mice.Molecules,2014, 19(1), 291-305 (SCI, IF 2.416)

48. Catherine P. Bondonno,Xingbin Yang, Kevin D. Croft, Michael J. Considine, Natalie C. Ward, Lisa Rich, Ian B. Puddey, Ewald Swinny, Aidilla Mubarak, Jonathan M Hodgson*. Flavonoid-rich apples and nitrate-rich spinach augment nitric oxide status and improve endothelial function in healthy men and women: a randomised controlled trial.Free Radical Biology & Medicine,2012, 52(1), 95-102 (SCI二区, IF 5.271)

49. Tong Wang,Xingbin Yang, Dongying Wang, Yadong Jiao, Yu Wang, Yan Zhao*. Analysis of compositional carbohydrates in polysaccharides and foods by capillary zone electrophoresis.Carbohydrate Polymers,2012, 88(2), 754-762 (SCI, IF 3.479)

50. Catherine P Bondonno*, Kevin D Croft, Ian B Puddey, Michael J Considine,Xingbin Yang, Natalie C Ward, Jonathan M Hodgson. Nitrate causes a dose-dependent augmentation of nitric oxide status in healthy women.Food & Function,2012, 3, 522-527 (SCI二区, IF 2.694)

2.孔庆军副教授

1)主持和参与科研项目

[1] 新疆酿酒葡萄中白藜芦醇二聚体异构体及类似物淬灭单线态氧(1O2)微量成分及其机制研究(21362028),国家自然科学基金,2014.01-2017.12,主持;

[2] 新疆酿酒葡萄紫檀防御酸腐病的机制研究(31460411),国家自然科学基金,2015.1-2018.12,合作主持;

[3] 酿酒葡萄紫檀茋与酸腐病互作分子机制研究(1110010591)陕西师范大学“学术骨干”人才引进项目,2015.1-2016.12,主持;

[4] 酿酒葡萄中白藜芦醇类筛选及抗氧化机制研究,中央高校基本科研业务费陕西师范大学自由探索项目(GK201603095),2016-2017,主持;

[5] 表达双价抗菌肽基因的重组酵母对几种新疆特色水果采后病害的防治及防治机理研究(312604402),国家自然科学基金,2013.1-2016.12,主研;

[6] 桃果实内酯类香气物质的生物合成及其调控机制研究(31260467), 国家自然科学基金2013.1-2016.12,主研。

2)代表性相关研究论文

1.Kong qingjun, Liang zhuo, Xiong jie, Li hongbin,Ren xueyan. Overexpression of the bivalent antibacterial peptide genes in Pichia pastoris delays sourrot in citrus fruit and induces Geotrichum Citri-aurantii cell apoptosis, Food Biotechnology, 2016, Accept. DOI:10.1080/08905436.2016.1165695 (IF=0.511)

2.Qingjun Kong, Xueyan Ren, Ruilin Hu, Xuefeng Yin, Guoshan Jiang,Yuanjiang Pan, Isolation and puri?cation of antioxidative two isomers of resveratroldimer from the wine grape by counter-current chromatography, Journal of Separation Science, 2016, Accept. (IF=2.737)

3. 余兴,孔庆军,任雪艳,三种精油对水果病原菌的细菌效果研究, 食品与生物技术学报,接收,2016.

4.Kong QJ, Ren XY, Sun CR, Pan YJ*, Identi?cation of isomers of resveratrol dimer and their analogues from wine grapes by HPLC/MSnand HPLC/DAD-UV, Food Chemistry,127(2),727-734,2011. (IF= 3.655)

5.Kong QJ,Ren XY, Jiang LY, Pan YY, Sun CR*, Scirpusin A, a hydroxystilbene dimer from Xinjiang wine grape, acts as an effective singlet oxygen quencher and DNA damage protector, Journal of the Science of Food and Agriculture, 90(5), 823-828, 2010. (IF=1.436)

6. Hu CF,Kong QJ, Yang DY, Pan YJ*, Isolation and structural characterization of a novel galactomannan from Eremurus anisopterus (Ker. et Kir) Regel roots, Carbohydrate Polymers, 84(1), 402–406, 2011.

7. Ren XY,Kong QJ, Zhou CT, Wang HL, Yu T, Zheng XD*, Control of postharvest decay on citrus fruit by Pichia pastoris recombinant strains expressing cecropin A antifungal peptide. Food Chemistry, 131(3), 796–801, 2012. (IF= 3.655)

8. Ren XY,Kong QJ, Wang P, Jiang F, Wang HL, Yu T, Zheng XD*, Molecular cloning of a PR-5 like protein gene from cherry tomato and analysis of the response of this gene to abiotic stresses, Molecular Biology Reports, 38(2), 801–807, 2011. (IF= 2.929)

9. Ren XY,Kong QJ, Wang HL, Yu T, Zhou WW, Zheng XD*, Control of apple blue mold by Pichia pastoris recombinant strains expressing cecropin A, Bioprocess and Biosystems Engineering, 35(5), 761-767, 2011. (IF= 1.809)

10.孔庆军,任雪艳,祝建波,李卓夫,朱新霞, 抗病基因转化伽师瓜研究,东北农业大学学报,39(1), 67-70, 2008。

11.孔庆军, 任雪艳、祝建波, 新疆伽师瓜高效再生系统建立及抗真菌病基因转化,西北农业学报,17(2), 207---211, 217, 2008。

3.邵红军副教授

1)主持或参加科研项目

[1] 中国博士后科学基金面上资助项目,2015M580811,EOPs 靶向脂筏/NF-κB通路的炎症调节机制与构效研究,2015/11-2017/11,8万,在研,主持

[2] 中央高校基本科研业务费专项资金项目,GK261001177,竹荪胞外抑菌物质定向诱导发现与其分子机理研究,2013/01-2015/12,5万,已结题,主持

[3] 国家自然科学基金青年项目,31100256,野八角萜类分子库的构建和用线虫模型的活性分子快速筛选,2012/01-2014/12,23万,已结题,参加

[4] 高等学校博士学科点专项科研基金(新教师类),20100202120009,高等真菌炭球菌潜在活性次级代谢产物的诱导与发现,2011/01-2013/12,3.6万,已结题,主持

2)代表性相关研究论文

1.Hongjun Shao, Jinboo Jeong, Kuijin Kim, Seongho Lee*. Anti-inflammatory activity of mushroom-derived hispidin through blocking of NF-kappaB activation.Journal of the Science of Food and Agriculture,2015, 95, 2482-2486.

2.Hongjun Shao, Zhiyuan Lou, Jinboo Jeong, Kuijin Kim, Jihye Lee, Seongho Lee*. Tolfenamic acid suppresses inflammatory stimuli-mediated activation of NF-kappaB signaling.Biomolecules & Therapeutics,2015, 23, 39-44.

3.Hongjun Shao, Xiangdong Qin, Jikai Liu*. Induced daldinins A-C with a new skeleton from cultures of the ascomyceteDaldinia concentrica.The Journal of Antibiotics,2008, 61, 115-119.

4.Hongjun Shao, Chunjiang Wang, Yun Dai, Fei Wang, Wanqiu Yang, Jikai Liu*. Pubescenone, a new marasmane sesquiterpenoid from the mushroomLactarius pubescens.Heterocycles,2007, 71, 1135-1139.

5.Hongjun Shao, Cheng Qing, Fei Wang, Jikai Liu*. A new cytotoxic lanostane triterpenoid from the basidiomyceteHebeloma versipelle.The Journal of Antibiotics,2005, 58, 828-831.

6. Hongjun Shao, Zejun Dong, Chunjiang Wan, Jikai Liu*. Dihydrobenzofurans from the culture broth of the basidiomyceteBondarzewia berkeleyi.Acta Botanica Yunnanica,2007, 29, 483-485.

7.Hongjun Shao, Lizheng Fang, Wanqiu Yang, Fei Wang, Jikai Liu*. A new steryl ester from the culture mycelia of the basidiomyceteAstraeus hygrometricus.Acta Botanica Yunnanica.2007, 29, 371-374.

8. Xiangdong Qin,Hongjun Shao, Zejun Dong, Jikai Liu*. Six new induced sesquiterpenes from the cultures of ascomyceteDaldinia concentrica.The Journal of Antibiotics, 2008, 61, 556-562.

9. Lizheng Fang,Hongjun Shao, Wanqiu Yang, Jikai Liu*. Two new azulene pigments from the fruiting bodies ofLactarius hatsudake.Helvetica Chimica Acta.2006, 89, 1463-1466.

10. Duqiang Luo,Hongjun Shao, Huajie Zhu, Jikai Liu*. Activityin vitroandin vivoagainst plant pathogenic fungi of grifolin isolated from the basidiomyceteAlbatrellus dispansus.Zeitschrift fur Naturforschung C,2005, 60, 50-56.

11. Lizheng Fang, Cheng Qing,Hongjun Shao, Jikai Liu*. Hypercillin D, a pigment fromShiraia bambusicola.The Journal of Antibiotics,2006, 59, 351-354.

12. Wanqiu Yang, Xiangdong Qin,Hongjun Shao, Lizheng Fang, Fei Wang, Zhihui Ding, Zejun Dong, Jikai Liu*. New phenyl-ethanediols from the culture broth ofBoletus edulis.Journal of Basic Microbiology,2007, 47, 191-193.

13.邵红军*, 程俊侠, 段玉峰. 花椒挥发油化学成分、生物活性及加工利用研究进展.食品科学,2013, 13, 319-322.

 

4.张忠讲师

1)主持项目

[1] 中央高校基本科研业务费专项资金项目,2016/01-2017/12,6万,主持

2)代表性相关研究论文

1.Zhong Zhang, Jinhua Li, Longwen Fu, Dongyan Liu, Lingxin Chen*. Magnetic molecularly imprinted microsensor for selective recognition and transport of fluorescent phycocyanin in seawater.Journal of Materials Chemistry A,2015, 3, 7437–7434.

2.Zhong Zhang, Jinhua Li, Xiaoyan Wang, Dazhong Shen, Lingxin Chen*.Quantum dots based mesoporous structured imprinting microspheres for the sensitive fluorescent detection of phycocyanin.ACS Appl. Mater. Interfaces,2015, 7, 9118–9127.

3.Zhong Zhang, Jinhua Li, Xingliang Song, Lingxin Chen*. Hg2+ion-imprinted polymers sorbents based on dithizone-Hg2+chelation for mercury speciation analysis in environmental and biological samples.RSC advances,2014, 4, 46444–46453.

4.Zhong Zhang, Lingxin Chen*, Fangfang Yang, Jinhua Li*. Uniform core-shell molecularly imprinted polymers: A correlation study between shell thickness and binding capacity.RSC advances,2014, 4, 31507–31514.

5Zhong Zhang, Jinhua Li, Junqing Fu, Lingxin Chen*. Fluorescent and magnetic dual-responsive coreshell imprinting microspheres strategy for recognition and detection of phycocyanin.RSC advances,2014, 4, 20677–20685.

6. Jinhua Li,Zhong Zhang, Shoufang Xu, Lingxin Chen*, Hua Xiong*. Label-free colorimetric detection of trace cholesterol based on molecularly imprinted photonic hydrogels.Journal of Materials Chemistry,2011, 21, 19267–19274.

7.Zhong Zhang, Shoufang Xu, Jinhua Li, Hua Xiong*, Lingxin Chen*. Selective solid-phase extraction of Sudan I in chilli sauce by single-hole hollow molecularly imprinted polymers.Journal of Agricultural and Food Chemistry,2012, 60, 180–187.

8.张忠, 胡居吾, 熊华*. 籼米多孔淀粉制备及吸附DHA微胶囊化. 食品工业科技,2012, 33, 211–213

5.李照讲师

1)主持项目

[1] 中央高校基本科研业务费专项资金项目, 2016/01-2017/12,6万,主持

2)代表性相关研究论文

1. Zhao Li, Xinghui Gao, Wen Shi, Xiaohua Li and Huimin Ma*,In vivodetection and imaging of nitroreductase in zebrafish by a new near-infrared fluorescence off-on probe. Biosens. Bioelectron., 2015, 63, 112-116. (SCI一区,影响因子: 6.409)

2. Zhao Li, Xiaohua Li*, Xinghui Gao, Yangyang Zhang, Wen Shi and Huimin Ma*, Nitroreductase Detection and Hypoxic Tumor Cell Imaging by a Designed Sensitive and Selective Fluorescent Probe, 7-[(5-Nitrofuran-2-yl)methoxy]-3H-phenoxazin-3-one.Anal. Chem., 2013, 85, 3926-3932. (SCI二区,影响因子: 5.636)

3. Zhao Li, Xinghui Gao, Wen Shi, Xiaohua Li and Huimin Ma*, 7-((5-Nitrothiophen-2-yl)methoxy)-3H-phenoxazin-3-one as a spectroscopic off-on probe for highly sensitive and selective detection of nitroreductase.Chem. Commun., 2013, 49, 5859-5861. (SCI二区,影响因子: 6.834)

4. Zhao Li, Huimin Ma*, Nitroreductase Detection and Hypoxic Tumor Cell Imaging by a Designed Fluorescent Probe.Chinese J. Anal. Chem.2013, 41, 963.

5. Zhao Li, Huimin Ma*, Progress in Resorufin-based Spectroscopic Probes.Imaging Science and Photochemistry, 2014, 32, 60-68.

6. 马会民,李照. 一种细菌硝基还原酶检测试剂盒及其专用荧光探针. 专利号: 201310174866.X.

7. 马会民, 陈巍,李照, 史文. 过氧化苯甲酰快速检测试剂盒. 专利号: 201110436046.4.

8. 马会民, 陈巍, 史文,李照. 一种简便快速检测面粉中过氧化苯甲酰含量的方法.专利号: 201110111407.8.

9. Wei Chen,Zhao Li,Wen Shi and Huimin Ma*, A new resorufin-based spectroscopic probe for simple and sensitive detection of benzoyl peroxideviadeboronation.Chem. Commun., 2012, 48, 2809-2811.

10. Lihong Li,Zhao Li, Wen Shi*, Xiaohua Li and Huimin Ma*, A Sensitive and Selective Near-Infrared Fluorescent Off-On Probe and Its Application to Imaging Different Levels of β-Lactamase in Staphylococcus Aureus.Anal. Chem., 2014, 86, 6115-6120.

11. Qiongqiong Wan, Yanchao Song,Zhao Li, Xinghui Gao and Huimin Ma*, In vivo monitoring of hydrogen sulfide using a cresyl violet-based ratiometric fluorescence probe.Chem. Commun.,2013, 49, 502-504.

12. Wei Chen, Wen Shi,Zhao Liand Huimin Ma*, Simple and fast fluorescence detection of benzoyl peroxide in wheat flour by N-methoxy rhodamine-6G spirolactam based on consecutive chemical reactions.Anal. Chim. Acta, 2011, 708,84-88.

13. Xinghui Gao, Qiongqiong Wan,Zhao Liand Huimin Ma*, Detection of glucose via enzyme-coupling reaction based on a DT-diaphorase fluorescence probe.Talanta, 2014, 120, 456-461.

6.林德慧

(1) 主持项目

[1] 中国博士后科学基金面上资助项目,2015/12-2017/12,8万,在研,主持

[2] 中央高校基本科研业务费专项资金项目,2016/01-2017/12,6万,主持

2)代表性相关研究论文

1.Lin, Dehui, Lopez-Sanchez, Patricia, Gidley, Michael J.*.Interactions of pectins with celllose during its synthesis in the absence of calcium. Food Hydrocolloids, 2016, 52, 57-68.

2.Lin, Dehui, Li, Rui, Lopez-Sanchez, Patricia, Li, Zhixi*. Physical properties of bacterial cellulose aqueous suspensions treated by high pressure homogenizer, Food Hydrocolloids, 2015, 44: 435-442.

3.Lin, Dehui, Lopez-Sanchez, Patricia, Gidley, Michael J.*. Binding of arabinan or galactan during cellulose synthesis is extensive and reversible, Carbohydrate Polymers, 2015, 126: 108-121.

4.Lin, Dehui,Lopez-Sanchez, Patricia, Li, Rui, Li, Zhixi*. Production of bacterial cellulose by Gluconacetobacter hansenii CGMCC 3917 using only waste beer yeast as nutrient source, Bioresource Technology, 2014, 151: 113-119.

5.Lin, Dehui, Wang, Nan, Li, Zhixi*, Li, Yan.Characterizations of Bacterial Cellulose Producing Strain Gluconoacetobacter hansenii CGMCC3917, Journal of Bioprocessing & Biotechniques, 2014, 4: 1-6.